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Enpp/Carbonic anhydrase-IN-1
$80 – $650
Products Details
Product Description
– Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent Enpp and carbonic anhydrase inhibitor with IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 μM for NPP1, NPP2, NPP3, CA-II, CA-IX respectively. Enpp/Carbonic anhydrase-IN-1 shows antiproliferative activity for cancer cells and low cytotoxic against normal cells. Enpp/Carbonic anhydrase-IN-1 induces Apoptosis[1].
Web ID
– HY-151916
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H25NO4S
References
– [1]Afnan I.Shahin, et al. Design and synthesis of new adamantyl derivatives as promising antiproliferative agents. European Journal of Medicinal Chemistry, 2022.
CAS Number
– 2883495-35-8
Molecular Weight
– 411.51
Compound Purity
– 99.57
SMILES
– O=S(C1=CC=CC=C1)(OC2=CC=C(C=C2)NC(C34CC5CC(C4)CC(C3)C5)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic;warming;heat to 50°C)
Target
– Apoptosis;Carbonic Anhydrase;Phosphodiesterase (PDE)
Isoform
– CA â…¡;CA â…¨
Pathway
– Apoptosis;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
