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Products Details
Product Description
– MRS4596 is a potent and selective P2X4 receptor antagonist with an IC50 value of 1.38 μM for human P2X4 receptor. MRS4596 has neuroprotective and neuro-rehabilitative activities in ischemic stroke model. MRS4596 can be used in research of ischemic stroke [1].
Web ID
– HY-151546
Shipping
– Room temperature
Molecular Formula
– C21H14N5NaO3S
References
– [1]Toti KS, et al. Structure-Activity Relationship and Neuroprotective Activity of 1,5-Dihydro-2H-naphtho[1,2-b][1,4]diazepine-2,4(3H)-diones as P2X4 Receptor Antagonists. J Med Chem. 2022 Sep 23.
Molecular Weight
– 439.42
SMILES
– O=C(C1)NC(C2=CC=C(C=C2C=C3)C)=C3N(C4=CC=NC(C([N-]5)=NOC5=S)=C4)C1=O.[Na+]
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– P2X Receptor
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
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