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SIRT2-IN-10

Products Details

Product Description

– SIRT2-IN-10 (Compound 12) is a potent SIRT2 inhibitor with an IC50 of 1.3 μM. SIRT2-IN-10 can be used for the research of cancer and neurodegenerative disease[1].

Web ID

– HY-151522

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C28H21N5OS

References

– [1]Shengyong Yang, et al. The purposes of 5H- [1,2,4] triazine [5,6-b] indole derivatives of 3 substitutions. Patent CN108309982A.

CAS Number

– 296793-09-4

Molecular Weight

– 475.56

SMILES

– O=C(CSC1=NC2=C(C(C=CC=C3)=C3N2CC4=CC=CC=C4)N=N1)NC5=C(C=CC=C6)C6=CC=C5

Clinical Information

– No Development Reported

Research Area

– Cancer; Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Sirtuin

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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