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Products Details
Product Description
– Cav 3.2 inhibitor 3 (Compound 4) is a potent Cav3.2 T-type Ca2+ channel inhibitor with an IC50 of 0.1534 μM, and has little binding affinity to D2 receptors[1].
Web ID
– HY-151452
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C32H37N3O2
References
– [1]Kasanami Y, et al. Discovery of pimozide derivatives as novel T-type calcium channel inhibitors with little binding affinity to dopamine D2 receptors for treatment of somatic and visceral pain. Eur J Med Chem. 2022 Aug 27;243:114716.
CAS Number
– 2878598-69-5
Molecular Weight
– 495.66
SMILES
– O=C1N(C2CCN(C(CCCC3=CC=CC=C3)=O)CC2)C4=CC=CC=C4N1CCCCC5=CC=CC=C5
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Calcium Channel
Isoform
– T-type calcium channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
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