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DPP-4-IN-1

Products Details

Product Description

– DPP-4-IN-1 (compound d1) is a potent DPP-4 (dipeptidyl peptidase 4) inhibitor, with an IC50of 49 nM. DPP-4-IN-1 is a structurally analogs of Alogliptin (HY-A0023A). DPP-4-IN-1 can be used for diabetes research[1].

Web ID

– HY-151383

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C19H19ClN6

References

– [1]Shen J, et al. Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors. Eur J Med Chem. 2020 Dec 15;208:112850.

CAS Number

– 2215027-46-4

Molecular Weight

– 366.85

SMILES

– ClC1=NC2=CC=NN2C(N3C[C@@H](CCC3)N)=C1CC4=C(C=CC=C4)C#N

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Dipeptidyl Peptidase

Isoform

– DPP-4

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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