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Products Details
Product Description
– BTK-IN-16 is a dual inhibitor of BTK wild type and C481S mutant of Bruton’s tyrosine kinase (BTK) with IC50s of 5.1 and 4.1 μM. BTK-IN-16 can be used for the research of autoimmune diseases and chronic lymphocytic leukemia[1].
Web ID
– HY-151211
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C15H14N4O2
References
– [1]Kim T, et al. Two-Track Virtual Screening Approach to Identify the Dual Inhibitors of Wild Type and C481S Mutant of Bruton’s Tyrosine Kinase. J Chem Inf Model. 2022 Aug 24.
CAS Number
– 2883232-92-4
Molecular Weight
– 282.30
SMILES
– COC1=CC(C(C=C1OC)=NC=N2)=C2NC3=CC=CN=C3
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Btk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
