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Product Description
– P2X7 receptor antagonist-2 is a potent P2X7 receptor antagonist with a pIC50 value of 6.5-7.5. P2X7 receptor antagonist-2 has efficacy of combating neuroinflammation[1].
Web ID
– HY-150059
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H18Cl2N2O2
References
– [1]Steadman JGA, et, al. 5-oxo-3-pyrrolidinecarboxamide derivatives as p2x7 modulators. WO2009077559A2
CAS Number
– 851269-75-5
Molecular Weight
– 377.26
SMILES
– ClC1=CC(Cl)=C(CNC(C2CN(C(C2)=O)CC3=CC=CC=C3)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– P2X Receptor
Isoform
– P2X7 Receptor
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
