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Products Details
Product Description
– DS43260857 is a potentNaV1.7inhibitor, which has a high inhibitory effect on both human and mouse NaV1.7. The IC50 values of DS43260857 for hNaV1.1, hNaV1.5, hNaV1.7, mNaV1.7 are 6.6, 14, 0.015 and 0.061 μM, respectively[1].
Web ID
– HY-149994
Shipping
– Room temperature
Molecular Formula
– C19H16F3N3O3S
References
– [1]Narayan Karanjule, et al. N-Aryl Indoles as a Novel Class of Potent NaV1.7 Inhibitors. ACS Med Chem Lett. 2023 May 24;14(6):788-793.
CAS Number
– 1612158-07-2
Molecular Weight
– 423.41
SMILES
– CC1=CN(C2=CC(C(F)(F)F)=CN=C2)C3=C1C=C(C(NS(C4CC4)(=O)=O)=O)C=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Sodium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
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