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Products Details
Product Description
– GPX4-IN-4 (Compound 24) is a potent GPX4 inhibitor. GPX4-IN-4 can be used for the research of cancer[1].
Web ID
– HY-149923
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H21ClN2O5S
References
– [1]Randolph JT, et al. Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo. J Med Chem. 2023 Mar 23;66(6):3852-3865.
CAS Number
– 2920221-53-8
Molecular Weight
– 460.93
SMILES
– COC([C@H]1CC2=C([C@@H](N1C(CCl)=O)C3=CC=C(C=C3)S(C)(=O)=O)NC4=CC=CC=C42)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Glutathione Peroxidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
