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Products Details
Product Description
– DDO-8926 is a potent and selective BET inhibitor that can significantly reduce mechanical hypersensitivity by inhibiting the expression of pro-inflammatory cytokines and reducing excitability for neuropathic pain research[1].
Web ID
– HY-149863
Shipping
– Room temperature
Molecular Formula
– C20H21FN6O2S
References
– [1]Xuetao Chen, et al. Discovery of 1H-Imidazo[4,5-b]pyridine Derivatives as Potent and Selective BET Inhibitors for the Management of Neuropathic Pain. J Med Chem. 2023 Jul 13;66(13):8725-8744.Â
Molecular Weight
– 428.48
SMILES
– CC1=NN(C(C)=C1C2=C(C(C3=C4NC=NC4=NC=C3)=CC(NS(CC)(=O)=O)=C2)F)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Reference compound
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