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Products Details
Product Description
– p38 Kinase inhibitor 5 (AA6) is a potent p38 kinase inhibitor with an IC50 of 403.57 nM. p38 Kinase inhibitor 5 has anti-inflammatory activity[1].
Web ID
– HY-149850
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H23F3N4O2
References
– [1]Archana Awasthi, et al. Synthesis, In Silico Studies, and In Vitro Anti-Inflammatory Activity of Novel Imidazole Derivatives Targeting p38 MAP Kinase. ACS Omega. 2023 May 12;8(20):17788-17799.
CAS Number
– 2929285-29-8
Molecular Weight
– 444.45
SMILES
– O=C(NC1=CC=C(C)C=C1C)C(NC(CN2C=C(C(F)(F)F)N=C2)=O)CC3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– p38 MAPK
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
