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Products Details
Product Description
– AKT-IN-18, an inhibitor of Akt, inhibits Akt with an IC50 of 69.45 μΜ in A549 cells. AKT-IN-18 induces apoptosis and can be used in non-small cell lung cancer study[1].
Web ID
– HY-149842
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H14ClN5O2S
References
Р[1]Erd̦nmez B,et.al. Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy. ACS Omega. 2023 May 24;8(22):20056-20065.
Molecular Weight
– 411.86
SMILES
– O=C(N/N=C/C1=CC=C(N2C=CN=C2)C=C1)CSC3=NC4=CC(Cl)=CC=C4O3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Akt;Apoptosis
Isoform
– Akt
Pathway
– Apoptosis;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
