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Products Details
Product Description
– Aurora Kinase Inhibitor-12 (Compound 1a ) is the inhibitor of aurora kinase which is a key enzyme that is implicated in tumor growth[1].
Web ID
– HY-149694
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C28H20BrN5O3S2
References
– [1]Bathula, Sivakumar, et al. 2-Amino Thiazole Derivatives as Prospective Aurora Kinase Inhibitors against Breast Cancer: QSAR, ADMET Prediction, Molecular Docking, and Molecular Dynamic Simulation Studies. ACS Omega (2023)
Molecular Weight
– 618.52
SMILES
– OC1=C(/C=C2N=C(C3=CC=CC=C3)N(C(NCC(NC4=C(C5=CC=C(Br)C=C5)SC=N4)=O)=S)C2=O)C=CC=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Aurora Kinase
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
