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Products Details
Product Description
– α-Glucosidase-IN-36 (compound 5g) is a potent α-glucosidase inhibitor, with an IC50 of 6.69 ± 0.18 μM, Ki and Kis of 1.65 μM and 4.54 μM, respectively. α-Glucosidase-IN-36 may inhibit α-glucosidase activity by binding with its active site as well as changing the secondary structure of α-glucosidase. α-Glucosidase-IN-36 can be used for type 2 diabetes mellitus (T2DM) research[1].
Web ID
– HY-149579
Shipping
– Room temperature
Molecular Formula
– C26H24BrN5O3S
References
– [1]Luo S, et al. Design, synthesis, biological evaluation, and docking study of new triazole-phenylacetamide derivatives as α-glucosidase inhibitors. Bioorg Chem. 2023 Sep 6;141:106844.
Molecular Weight
– 566.47
SMILES
– BrC1=CC=C(/C=N/N2C(COC3=CC=CC=C3)=NN=C2SCC(NC4=CC=C(OCC)C=C4)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Glucosidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
