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MMP13-IN-4
SKU
HY-149377-Get quote
Category Reference compound
Tags Metabolic Disease, Metabolic Enzyme/Protease, MMP
Products Details
Product Description
– MMP13-IN-4 (compound 13) is a potent and selective inhibitor of MMP-13 (IC50=14.6 μM),involved in osteoarthritis (OA)[1].
Web ID
– HY-149377
Shipping
– Room temperature
Molecular Formula
– C21H17BrN4O5
References
– [1]Cuffaro D, et al. Identification of N-Acyl Hydrazones as New Non-Zinc-Binding MMP-13 Inhibitors by Structure-Based Virtual Screening Studies and Chemical Optimization. Int J Mol Sci. 2023 Jul 4;24(13):11098.
CAS Number
– 514855-02-8
Molecular Weight
– 485.29
SMILES
– O=C(N/N=C(C1=CC=C(NC(C2=CC=C(Br)O2)=O)C=C1)C)CC3=CC=C([N+]([O-])=O)C=C3
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– MMP
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.