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Products Details
Product Description
– NT160 is a highly potent class-IIa HDAC inhibitor with an IC50 value of 0.046 μM. NT160 can be used for the research of central nervous system diseases[1].
Web ID
– HY-149285
Shipping
– Room temperature
Molecular Formula
– C21H21F3N4O2
References
– [1] Turkman N, et al. Design, synthesis, biochemical evaluation, radiolabeling and in vivo imaging with high affinity class-IIa histone deacetylase inhibitor for molecular imaging and targeted therapy. Eur J Med Chem. 2022;228:114011.
CAS Number
– 1418293-40-9
Molecular Weight
– 418.41
SMILES
– O=C(N[C@H](C)CN(CC1=CC=CC=C1)C)C2=CC=C(C=C2)C3=NOC(C(F)(F)F)=N3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– HDAC
Isoform
– HDAC4;HDAC5;HDAC7;HDAC9
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
