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Products Details
Product Description
– JNK3 inhibitor-6 (Compound A53) is a selective JNK3 Inhibitor (IC50=78 nM). JNK3 inhibitor-6 has neuroprotective effect, and can used for research of neurodegenerative diseases[1].
Web ID
– HY-149268
Shipping
– Room temperature
Molecular Formula
– C24H21Cl2N5O3S
References
– [1]Li Z, et al. The structure-based optimization of 3-substituted indolin-2-one derivatives as potent and isoform-selective c-Jun N-terminal kinase 3 (JNK3) inhibitors and biological evaluation. Eur J Med Chem. 2023 Mar 15;250:115167.
Molecular Weight
– 530.43
SMILES
– CN1CCC(CC1)C(NC2=CC3=C(NC(/C3=C4S/C(NC4=O)=N/C5=CC=CC(Cl)=C5Cl)=O)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– JNK
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
