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Products Details
Product Description
– SLF1081851 (TFA) is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM). SLF1081851 (TFA) plays a key role in development and immune system[1][2].
Web ID
– HY-149004A
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H34F3N3O3
References
– [1]Fritzemeier R, et al. Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors. J Med Chem. 2022 Jun 9;65(11):7656-7681. |[2]Lynch Kevin R, et al. Preparation of oxadiazoles as inhibitors of spinster homolog 2 (SPNS2) for use in therapy: World Intellectual Property Organization, WO2022056042[P]. 2022-03-17.
CAS Number
– 2763730-98-7
Molecular Weight
– 457.53
SMILES
– NCCCC1=NC(C2=CC=C(CCCCCCCCCC)C=C2)=NO1.O=C(O)C(F)(F)F
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– LPL Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
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