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LY2880070

Products Details

Product Description

– LY2880070 is an orally active CHK1 inhibitor. LY2880070 can be used as an anticancer agent for combination with DNA damaging agents[1].

Web ID

– HY-148962

Shipping

– Room temperature

Molecular Formula

– C19H23N7O2

References

– [1]Quincy S, et al. A phase Ib study of oral Chk1 inhibitor LY2880070 in combination with gemcitabine in patients with advanced or metastatic cancer. Journal of Clinical Oncology 2020 38:15_suppl, 3581.

CAS Number

– 1375637-35-6

Molecular Weight

– 381.43

SMILES

– COC1=C(C=CC(C)=N1)C2=CC(NC3=NC(O[C@@H]4CCCNC4)=CN=C3)=NN2

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Checkpoint Kinase (Chk)

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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