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Products Details
Product Description
– Cavα2δ1&NET-IN-3 (example 216) is an inhibitor of the subunit α2δ of voltage-gated calcium channels (VGCC) and noradrenaline transporter (NET). Cavα2δ1&NET-IN-3 has Kis of 100-500 nM for human α2δ-1 subunit of Cav2.2 calcium channel and NET, respectively[1].
Web ID
– HY-148866
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C24H30N6O2S
References
– [1]Félix CUEVAS-CORDOBÉS, et al. Tetrahydropyrimidodiazepine and tetrahydropyridodiazepine compounds for treating pain and pain related conditions. WO2017191304A1.
CAS Number
– 2143584-82-9
Molecular Weight
– 466.60
SMILES
– O=C1C2=CN=C(NCC)N=C2N(CCN1C3=CC(O[C@H](C4=CC=CS4)CCNC)=CC=C3)C
Clinical Information
– No Development Reported
Research Area
– Endocrinology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Calcium Channel
Isoform
– Calcium Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
