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Products Details
Product Description
– AMPK activator 10 is an orally active, potent AMPK activator with EC150 of 44.3 nM by cell-ELISA. AMPK activator 10 increases the phosphorylation levels of ACC. AMPK activator 10 exhibits a glucose lowering effect[1].
Web ID
– HY-148684
Shipping
– Room temperature
Molecular Formula
– C24H26ClFN4O6
References
– [1]Yuusuke Tamura, et al. Identification of novel benzimidazole derivatives as highly potent AMPK activators with anti-diabetic profiles. Bioorg Med Chem Lett. 2023 Jan 1;79:129059.
CAS Number
– 1914176-03-6
Molecular Weight
– 520.94
SMILES
– COCCOC1=CC(F)=C(C(CC2)=C1)[C@H]2NC3=C(Cl)C=C(NC(O[C@H]4[C@]5([H])[C@]([C@@H](CO5)O)([H])OC4)=N6)C6=N3
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– AMPK
Isoform
– AMPK
Pathway
– Epigenetics;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
