Download Files:
Products Details
Product Description
– Sirtuin modulator 4 (compound 12) is a sirtuin modulator. Sirtuin modulator 4 shows inhibitory effect to SIRT1 with an EC50 value of 51-100 μM. Sirtuin modulator 4 may be used for the research of increasing the lifespan of a cell, and preventing a wide variety of diseases and disorders including, for example, diabetes, obesity, neurodegenerative diseases, cardiovascular diseases, inflammation and cancer[1].
Web ID
– HY-148312
Shipping
– Room temperature
Molecular Formula
– C18H10N2O2S
References
– [1]Milburn Michael, et al. Fused heterocyclic compounds and their use as sirtuin modulators. US7998974. 2011.
CAS Number
– 327104-77-8
Molecular Weight
– 318.35
SMILES
– N#CC(C(C1=CC2=C(C=CC=C2)O1)=O)C3=NC4=C(S3)C=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Sirtuin
Isoform
– SIRT1
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
