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Products Details
Product Description
– IGUANA-1 free base (STL5-T-0057) is an selective ALDH1 B1 inhibitor with an IC50 value of 30 nM. IGUANA-1 free base inhibits cell growth of SW480 cells in adherent and spheroid conditions with IC50 values of 2.46 and 0.39 μM, respectively. IGUANA-1 free base can be used for the research of cancer[1].
Web ID
– HY-148243
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H24ClN3O2
References
– [1]Chen Jame Kenneth, et al. Preparation of substituted imidazolium or cyclic guanidine compounds as isoform-specific aldehyde dehydrogenase inhibitors for the treatment of cancer. WO2021257696 A1. 2021.
CAS Number
– 2756014-24-9
Molecular Weight
– 445.94
SMILES
– ClC1=CC(OC)=C(C2=CN(C3=NCCCN32)C4=CC=C(C5=C(OC)C=CC=C5)C=C4)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Aldehyde Dehydrogenase (ALDH)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
