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Products Details
Product Description
– PI4KIIIbeta-IN-11 is an inhibitor of PI4KIIIβ, with a mean pIC50 value of at least 9.1. PI4KIIIβ plays a key role in diseases research of RNA viruses and Plasmodium falciparum[1][2].
Web ID
– HY-148075
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C33H39N7O3
References
– [1]Kremer L, et al. Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß. Angew Chem Int Ed Engl. 2019 Nov 11;58(46):16617-16628. |[2]Barton Nicholas Paul, et al. Preparation of pyrazolopyrimidinamines derivatives as PI4kIII-beta inhibitors: World Intellectual Property Organization, WO2019141694. 2019-07-25.
CAS Number
– 2365241-79-6
Molecular Weight
– 581.71
SMILES
– CN1C(C2=CC=CC(CNC3=CC(C(C)(O)C)=NC4=C(C5=CC(C(N(C)[C@@H](C)CO)=O)=C(C=C5)C)C(C)=NN34)=C2)=NC=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– PI4K
Isoform
– PI4KIIIβ
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
