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Products Details
Product Description
– hCAI/II-IN-3 (compound 5b) is a potent dual hCA I/II inhibitor with Ki values of 51.25, 13.15 and 42.18 nM for hCA I, hCA II and hCA â…¨. hCAI/II-IN-3 possesses anti-hypoxic activity against acute mountain sickness (AMS) and low cellular activity[1].
Web ID
– HY-147923
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H18N4O4S2
References
– [1]Yang C, et al. N-Quinary heterocycle-4-sulphamoylbenzamides exert anti-hypoxic effects as dual inhibitors of carbonic anhydrases I/II. Bioorg Chem. 2020 Jul;100:103931.
CAS Number
– 2480283-93-8
Molecular Weight
– 394.47
SMILES
– O=C(C1=CSC(NC(C2=CC=C(S(=O)(N)=O)C=C2)=O)=N1)NC3CCCC3
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA â…¡;CA I
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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