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Products Details
Product Description
– hCAI/II-IN-2 (compound 2b) is a potent dual hCA I/II inhibitor with Ki values of 40.97, 15.15 and 61.88 nM for hCA I, hCA II and hCA â…¨. hCAI/II-IN-2 possesses anti-hypoxic activity against acute mountain sickness (AMS) and low cellular activity[1].
Web ID
– HY-147922
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C12H12N4O5S2
References
– [1]Yang C, et al. N-Quinary heterocycle-4-sulphamoylbenzamides exert anti-hypoxic effects as dual inhibitors of carbonic anhydrases I/II. Bioorg Chem. 2020 Jul;100:103931.
CAS Number
– 2480283-75-6
Molecular Weight
– 356.38
SMILES
– O=C(C1=NN=C(NC(C2=CC=C(S(=O)(N)=O)C=C2)=O)S1)OCC
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA â…¡;CA I
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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