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Products Details
Product Description
– Tubulin inhibitor 29 (compound 3c) is a potent tubulin inhibitor with an IC50 value of 1.2 µM. Tubulin inhibitor 29 shows antiproliferative effects with an IC50 value of 7.5 µM for MCF-7 cells. Tubulin inhibitor 29 inhibits tubulin assembly and bounds in the colchicine site[1].
Web ID
– HY-147888
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C12H8F2O2S2
References
– [1]Khodyuk RGD, et al. Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity. Bioorg Chem. 2020 Aug;101:104017.
CAS Number
– 2905-15-9
Molecular Weight
– 286.32
SMILES
– O=S(C1=CC=C(F)C=C1)(SC2=CC=C(F)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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