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Products Details
Product Description
– Nampt-IN-7 (compound GF8) is a potent NAMPT inhibitor, with an IC50 of 7.31 μM. Nampt-IN-7 also displays cytotoxic activity against human HepG2 hepatocellular carcinoma cell line with an IC50 of 24.28 μM[1].
Web ID
– HY-147756
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H21N5O3
References
– [1]Ozgencil F, et al. Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening. Bioorg Med Chem. 2020 Jan 1;28(1):115217.
CAS Number
– 1223378-42-4
Molecular Weight
– 379.41
SMILES
– CCOC(C1=CC=C(C=C1)NC(NCC2=CC(N3C=CN=C3C)=NC=C2)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– NAMPT
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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