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Products Details
Product Description
– Antitumor photosensitizer-3 (Compound I) is a chlorin derivative. Antitumor photosensitizer-3 induces tumor cells apoptosis and necrosis under 650 nm laser irradiation. Antitumor photosensitizer-3 exhibits lower skin photo-toxicity than positive reference m-THPC in vivo[1].
Web ID
– HY-147521
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C48H34N4O4
References
– [1]Gao YH, et al. Synthesis and pharmacological evaluation of chlorin derivatives for photodynamic therapy of cholangiocarcinoma. Eur J Med Chem. 2020 Mar 1;189:112049.
Molecular Weight
– 730.81
SMILES
– COC(C1(C2/C(N=C(C21)/C(C3=CC=CC=C3)=C4C=C/C(N/4)=C5C6=CC=CC=C6)=C(C7=CC=CC=C7)/C(N8)=CC=C8/C(C9=CC=CC=C9)=C%10C=CC5=N/%10)C(O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Necroptosis
Pathway
– Apoptosis
Product type
– Reference compound
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