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Vulolisib
$310 – $6,500
Products Details
Product Description
– Vulolisib is a potent and orally active phosphatidylinositol 3-kinase (PI3K) inhibitor, with IC50 values of 0.2 nM, 168 nM, 90 nM and 49 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively. Antiproliferative and antineoplastic activity[1].
Web ID
– HY-147419
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C18H19F2N5O3S
References
– [1]Xiaolan ZHAN, et al. Three fused ring derivative-containing salt or crystal form and pharmaceutical composition thereof. WO2021104146A1 (example 22)
CAS Number
– 2390105-79-8
Molecular Weight
– 423.44
Compound Purity
– 99.60
SMILES
– NC([C@H](C)NC1=CC=C(C2=NC(N3[C@@H](CSC3=O)C(F)F)=CN2CCO4)C4=C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PI3K
Isoform
– PI3Kα;PI3Kβ;PI3Kγ;PI3Kδ
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
