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Products Details
Product Description
– Bromodomain inhibitor-10 (compound 128) is a potent bromodomain inhibitor with Kds of 15.0, 2500 nM for BRD4-1 and BRD4-2, respectively. Bromodomain inhibitor-10 inhibits the production of IL12p40[1].
Web ID
– HY-147375
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H20N4O3
References
– [1]Jimmi GERNER SEITZBERG, et al. Compounds active towards bromodomains. WO2016016316A1
CAS Number
– 1870849-58-3
Molecular Weight
– 364.40
SMILES
– CC1=CC(NC2=C1C=C(NC(C3=C(N4CCOCC4)N=CC=C3)=O)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Isoform
– BRD4
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
