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Products Details
Product Description
– NMDA receptor potentiator-1 (Compound 1368) is a subunit selective NMDA receptor potentiator with IC50s of 4 μM and 5 μM against NR2C and NR2D expression, respectively[1].
Web ID
– HY-147352
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C26H26ClNO5
References
– [1]Stephen F. Traynelis, et al. Subunit selective NMDA receptor potentiators for the treatment of neurological conditions. Patent US8822462.
CAS Number
– 486427-18-3
Molecular Weight
– 467.94
SMILES
– O=C(N1CCC2=CC(OC)=C(C=C2C1COC3=CC=C(C=C3)OC)OC)C4=CC=C(C=C4)Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– iGluR
Isoform
– NMDA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
