Download Files:
GSK-3β inhibitor 10
$120 – $390
Products Details
Product Description
– GSK-3β inhibitor 10 (compound 14a) is a highly potent GSK-3β inhibitor with an IC50 value of 80.5 nM. GSK-3β inhibitor 10 can be used for researching Alzheimer’s disease[1].
Web ID
– HY-147134
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C12H12N2O3S
References
– [1]Arfeen M, et al. Design, synthesis and biological evaluation of 5-benzylidene-2-iminothiazolidin-4-ones as selective GSK-3β inhibitors. Eur J Med Chem. 2016 Oct 4;121:727-736.
CAS Number
– 1198098-03-1
Molecular Weight
– 264.30
Compound Purity
– 98.04
SMILES
– COC(C=C1/C=C2C(N=C(S/2)N)=O)=C(C=C1)OC
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 25 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– GSK-3
Isoform
– GSK-3β
Pathway
– PI3K/Akt/mTOR;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
