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ZINC194100678
$315
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Products Details
Product Description
– ZINC194100678 is a potent PAK1 inhibitor with an IC50 value of 8.37 μM. ZINC194100678 can inhibit MDA-MB-231 cell proliferation. ZINC194100678 can be used for researching anticancer[1].
Web ID
– HY-146783
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C10H13N5O
References
– [1]Zhang J, et al. Design, synthesis and biological evaluation of 1H-pyrazolo [3,4-d]pyrimidine derivatives as PAK1 inhibitors that trigger apoptosis, ER stress and anti-migration effect in MDA-MB-231 cells. Eur J Med Chem. 2020;194:112220.
CAS Number
– 1995025-05-2
Molecular Weight
– 219.24
SMILES
– C12=NC=NC(NC3CCOCC3)=C1C=NN2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PAK
Isoform
– PAK1
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
