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Tubulin inhibitor 24

$316

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Products Details

Product Description

– Tubulin inhibitor 24 is a potent tubulin inhibitor. Tubulin inhibitor 24 inhibits tubulin polymerization. Tubulin inhibitor 24 induces cell cycle arrest at the G2/M phase in a concentration-dependent manner. Tubulin inhibitor 24 shows antitumor activity with no obvious toxicity[1].

Web ID

– HY-146711

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C22H21N3O3

References

– [1]Li G,et al. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities. Eur J Med Chem. 2020; 202:112519.

CAS Number

– 2415761-65-6

Molecular Weight

– 375.42

SMILES

– COC1=CC(C2=CC=NC3=CC(C4=CC=C(C=C4)C)=NN32)=CC(OC)=C1OC

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Microtubule/Tubulin

Pathway

– Cell Cycle/DNA Damage;Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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