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LpxC-IN-9

Products Details

Product Description

– LpxC-IN-9 (compound 19) is a potent LpxC inhibitor. LpxC-IN-9 has antibacterial and hypotensive effects[1]. LpxC-IN-9 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Web ID

– HY-146650

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C23H25N5O3S

References

– [1]Takeru Furuya, et al. N-Hydroxyformamide LpxC inhibitors, their in vivo efficacy in a mouse Escherichia coli infection model, and their safety in a rat hemodynamic assay. Bioorg Med Chem. 2020 Dec 15;28(24):115826.

CAS Number

– 2756125-46-7

Molecular Weight

– 451.54

SMILES

– CS[C@H](N(C=O)O)CN1N=NC2=C1C=CC(C#CC3=CC=C(C=C3)CN4CCOCC4)=C2

Clinical Information

– No Development Reported

Research Area

– Infection; Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– Bacterial

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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