Download Files:
HP210
$110 – $360
Products Details
Product Description
– HP210 is a selective glucocorticoid receptor modulator (SGRM). HP210 can inhibit the mRNA expression of IL-1β and IL-6. HP210 has the potential to study inflammation-related diseases[1].
Web ID
– HY-146564A
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Molecular Formula
– C22H19N3O2S2
References
– [1]Hu X, et al. Discovery of novel non-steroidal selective glucocorticoid receptor modulators by structure- and IGN-based virtual screening, structural optimization, and biological evaluation. Eur J Med Chem. 2022 Jul 5;237:114382.
CAS Number
– 728039-52-9
Molecular Weight
– 421.54
Compound Purity
– 98.96
SMILES
– O=C(C1=CC=C(CN2C(C3=C(NC2=S)C=CS3)=O)C=C1)NC(C)C4=CC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– Glucocorticoid Receptor
Pathway
– Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
