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Products Details
Product Description
– FAAH/MAGL-IN-3 (Compound 10) is an irreversible fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) dual inhibitor with IC50 values of 179 and 759 nM against FAAH and MAGL, respectively. FAAH/MAGL-IN-3 shows low PAMPA (Parallel Artificial Membrane Permeability Assay) permeability[1].
Web ID
– HY-146342
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H25N3O6S
References
– [1]Alan Fulp, et al. Design and synthesis of endocannabinoid enzyme inhibitors for ocular indications. Bioorg Med Chem Lett. 2022 Jul 15;68:128763.
CAS Number
– 2848719-34-4
Molecular Weight
– 447.50
SMILES
– CCCCC1=CC=C(C=C1)S(=O)(N2CCN(CC2)C(OC3=CC=C(C=C3)[N+]([O-])=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– FAAH;MAGL
Pathway
– Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
