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HIF-IN-1
SKU
HY-146144-10 mg
Category Reference compound
Tags Cancer, HIF/HIF Prolyl-Hydroxylase, Metabolic Enzyme/Protease
$130 – $1,100
Products Details
Product Description
– HIF-IN-1 (Compound 3c) is a hypoxia-inducible factor (HIF)-1 inhibitor. HIF-IN-1 suppresses HIF-1α protein accumulation without affecting the levels of HIF-1α mRNA. HIF-IN-1 shows no obvious cytotoxicity[1].
Web ID
– HY-146144
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H12N2O
References
– [1]Fuse S, et al. Design, synthesis, and evaluation of indeno[2,1-c]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activity. Bioorg Med Chem. 2020 Jan 1;28(1):115207.
CAS Number
– 2393928-76-0
Molecular Weight
– 260.29
Compound Purity
– 99.19
SMILES
– O=C(C1=C2C=NN1C3=CC=C(C)C=C3)C4=C2C=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– HIF/HIF Prolyl-Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.