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Carbonic anhydrase inhibitor 13

SKU HY-146010-Get quote Category Tags , ,

Products Details

Product Description

– Carbonic anhydrase inhibitor 13 (compound 7) is a potent carbonic anhydrase (CA) inhibitor, which features 3-methylthiazolo[3,2-a]benzimidazole moiety (as a tail) connected to the zinc anchoring benzenesulfonamide moiety via ureido linker[1].

Web ID

– HY-146010

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C17H15N5O3S2

References

– [1]Alkhaldi AAM, et al. 3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies. Eur J Med Chem. 2020 Dec 1;207:112745.

CAS Number

– 2488872-31-5

Molecular Weight

– 401.46

SMILES

– O=S(C1=CC=C(NC(NC2=C(C)N3C4=CC=CC=C4N=C3S2)=O)C=C1)(N)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Carbonic Anhydrase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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