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AGI-41998
$390 – $3,200
Products Details
Product Description
– AGI-41998 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A). AGI-41998 is a brain-penetrant compound. AGI-41998 has the potential for exploring the effects of SAM modulation in the central nervous system (CNS) and research of cancer disease[1].
Web ID
– HY-145778
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C22H16BrF3N4O2
References
– [1]Li M, et al. Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. J Med Chem. 2022;65(6):4600-4615.
CAS Number
– 2377492-26-5
Molecular Weight
– 505.29
Compound Purity
– 99.88
SMILES
– O=C1C(C2=CC=C(Br)C=C2)=C3N=C(NCC(F)(F)F)N=CC3=CN1C4=CC=C(OC)C=C4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)
Target
– Somatostatin Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
