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Pomalidomide-C12-NH2 (hydrochloride)
$180 – $1,200
Products Details
Product Description
– Pomalidomide-C12-NH2 hydrochloride is the E3 ligase ligand-linker conjugate of PROTAC KRAS G12C degrader-1 (HY-139186). PROTAC KRAS G12C degrader-1 is a Cereblon-based KRASG12C degrader[1].
Web ID
– HY-145615
Storage Temperature
– -20°C (Powder, protect from light)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H37ClN4O4
References
– [1]Zeng M, et, al. Exploring Targeted Degradation Strategy for Oncogenic KRAS G12C. Cell Chem Biol. 2020 Jan 16;27(1):19-31.e6.
CAS Number
– 2862774-02-3
Molecular Weight
– 493.04
Compound Purity
– 97.09
SMILES
– NCCCCCCCCCCCCNC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
