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Products Details
Product Description
– Onfasprodil is negative allosteric modulator of NR2B. Onfasprodil in combination with GABA receptor regulator has the potential for the research of Alzheimer’s disease (extracted from patent CN111481543A)[1].
Web ID
– HY-145585
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C20H23FN2O3
References
– [1]Liu, Shanglian, et al. Use of NR2B negative allosteric modulators in combination with GABA receptor modulators for the preparation of a medicament for the treatment of Alzheimer’s disease. Patent CN111481543A.
CAS Number
– 1892581-29-1
Molecular Weight
– 358.41
SMILES
– O[C@H](C1=CC=C(C=N1)O)CN(C2)C[C@](C3)([H])[C@@]2([H])C[C@H]3OC4=C(C=CC=C4)F
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– iGluR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
