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Products Details
Product Description
– HDAC-IN-26 is a highly selective class I HDAC inhibitor with an EC50 value of 4.7 nM.
Web ID
– HY-145350
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C24H28FN5O3
References
– [1]Liu J, Kelly J, Yu W, Clausen D, Yu Y, Kim H, Duffy JL, Chung CC, Myers RW, Carroll S, Klein DJ, Fells J, Holloway MK, Wu J, Wu G, Howell BJ, Barnard RJO, Kozlowski JA. Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for Clearance. ACS Med Chem Lett. 2020 Jun 22;11(7):1476-1483.
CAS Number
– 2410542-97-9
Molecular Weight
– 453.51
SMILES
– FC1=C(C=CC=C1)C2=CN=C([C@H](CCCCCC(C3=NOC=C3)=O)NC(C4CN(C4)C)=O)N2
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
