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Products Details
Product Description
– ARG1-IN-1 (example 1) is a human arginase 1 inhibitor with an IC50 of 29 nM[1].
Web ID
– HY-145331
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C11H21BN2O4
References
– [1]Mitcheltree MJ, et al. Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. ACS Med Chem Lett. 2020 Mar 23;11(4):582-588.
CAS Number
– 2376189-62-5
Molecular Weight
– 256.11
SMILES
– OB(O)CCC[C@H]1[C@@]2([H])[C@@](CNC2)([H])C[C@@]1(N)C(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Arginase
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
