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Products Details
Product Description
– GPBAR1-IN-3 (Compound 14) is a selective GPBAR1 agonist (EC50=0.17 μM) and a CysLT1R antagonist[1].
Web ID
– HY-145234
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H23NO2
References
– [1]Fiorillo B, et al. Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1. J Med Chem. 2021 Nov 12.
CAS Number
– 2760546-05-0
Molecular Weight
– 321.41
SMILES
– CC(CC)COC1=CC(OCC2=NC3=C(C=C2)C=CC=C3)=CC=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Others
Solubility
– 10 mM in DMSO
Target
– G protein-coupled Bile Acid Receptor 1;Leukotriene Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
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