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Products Details
Product Description
– Tubulin inhibitor 22 (compound 4c) is a potent inhibitor of tubulin with anti-angiogenesis and anti-cancer properties. Tubulin inhibitor 22 arrests MGC-803 cell cycle at G2/M phase. Tubulin inhibitor 22 dose-dependently causes Caspase-induced apoptosis of MGC-803 cells through mitochondrial dysfunction[1].
Web ID
– HY-144797
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H17BrFNO4
References
– [1]Sun M, et al. Identification of novel non-toxic and anti-angiogenic α-fluorinated chalcones as potent colchicine binding site inhibitors. J Enzyme Inhib Med Chem. 2022;37(1):339-354.
Molecular Weight
– 434.26
SMILES
– O=C(C1=CC(OC)=C(OC)C(OC)=C1)/C(F)=C/C2=CNC3=C2C=CC(Br)=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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