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Dual FAAH/sEH-IN-1

$567$1,700

Products Details

Product Description

– Dual FAAH/sEH-IN-1 (compound 3) is a high affinity dual sEH (soluble epoxide hydrolase) and FAAH (fatty acid amide hydrolase) inhibitor, with IC50 values of 9.6 and 7 nM, respectively. Dual FAAH/sEH-IN-1 shows antinociception against the inflammatory phase[1].

Web ID

– HY-144738

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C25H22ClN3O3S2

References

– [1]Wilt S, Kodani S, Valencia L, et al. Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorg Med Chem. 2021;51:116507.

CAS Number

– 2756099-59-7

Molecular Weight

– 512.04

SMILES

– O=C(C1CCN(CC1)S(=O)(C2=CC=CC=C2Cl)=O)NC3=CC=C(C=C3)C4=NC5=CC=CC=C5S4

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Epoxide Hydrolase;FAAH

Pathway

– Metabolic Enzyme/Protease;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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