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Products Details
Product Description
– Carbonic anhydrase inhibitor 5 is a potent and selective human carbonic anhydrase (hCA) inhibitor with IC50s of 42.9, 47,6 and 6.7 nM for hCA II, hCA IX and hCA XII, respectively[1].
Web ID
– HY-144639
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C24H20ClN3O3S
References
– [1]Swain B, et al. Exploration of 2-phenylquinoline-4-carboxamide linked benzene sulfonamide derivatives as isoform selective inhibitors of transmembrane human carbonic anhydrases. Eur J Med Chem. 2022;234:114247.
Molecular Weight
– 465.95
SMILES
– NS(=O)(C1=CC=C(C=C1)CCNC(C2=CC(C3=CC=CC=C3)=NC4=CC=C(C=C42)Cl)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA â…¡;CA â…¨;CA XII
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
