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Products Details
Product Description
– Neuropeptide Y Y1 receptor antagonist 1 (compound 39), a fluorescent probe, is a potent antagonist of neuropeptide Y Y1 receptor (Y1R), with a Ki of 0.19 nM[1].
Web ID
– HY-144603
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C62H70N10O10
References
– [1]Müller C, et, al. Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y 1 Receptor. J Med Chem. 2022 Mar 24;65(6):4832-4853.
CAS Number
– 2773476-40-5
Molecular Weight
– 1115.28
SMILES
– O=C(C1=CC(C(NCCCCOC2=CC=CC([C@@H](C(N[C@H](CCCN/C(N)=NC(NCCNC(CC)=O)=O)C(NCC3=CC=C(C=C3)O)=O)=O)C4=CC=CC=C4)=C2)=O)=CC=C1C5=C6C=C/C(C=C6OC7=C5C=CC(N(C)C)=C7)=[N+](C)/C)[O-]
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Neuropeptide Y Receptor
Isoform
– NPY Y1 receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Dye Reagents
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
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